SMAD3 Is Associated with the Total Burden of Radiographic Osteoarthritis: The Chingford Study

BACKGROUND: A newly-described syndrome called Aneurysm-Osteoarthritis Syndrome (AOS) was recently reported. AOS presents with early onset osteoarthritis (OA) in multiple joints, together with aneurysms in major arteries, and is caused by rare mutations in SMAD3. Because of the similarity of AOS to i...

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Main Authors: Aref-Eshghi, Erfan, Zhang, Yuhua, Hart, Deborah, Valdes, Ana M., Furey, Andrew, Martin, Glynn, Sun, Guang, Rahman, Proton, Arden, Nigel, Spector, Tim D., Zhai, Guangju
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031234/
https://ncbi.nlm.nih.gov/pubmed/24852296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097786
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