Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross

New systems genetics approaches are needed to rapidly identify host genes and genetic networks that regulate complex disease outcomes. Using genetically diverse animals from incipient lines of the Collaborative Cross mouse panel, we demonstrate a greatly expanded range of phenotypes relative to clas...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Gralinski, Lisa E., Ferris, Martin T., Aylor, David L., Whitmore, Alan C., Green, Richard, Frieman, Matthew B., Deming, Damon, Menachery, Vineet D., Miller, Darla R., Buus, Ryan J., Bell, Timothy A., Churchill, Gary A., Threadgill, David W., Katze, Michael G., McMillan, Leonard, Valdar, William, Heise, Mark T., Pardo-Manuel de Villena, Fernando, Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599853/
https://ncbi.nlm.nih.gov/pubmed/26452100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005504
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