Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants

BACKGROUND: In 2003, severe acute respiratory syndrome coronavirus (SARS-CoV) was identified as the etiological agent of severe acute respiratory syndrome, a disease characterized by severe pneumonia that sometimes results in death. SARS-CoV is a zoonotic virus that crossed the species barrier, most...

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Main Authors: Deming, Damon, Sheahan, Timothy, Heise, Mark, Yount, Boyd, Davis, Nancy, Sims, Amy, Suthar, Mehul, Harkema, Jack, Whitmore, Alan, Pickles, Raymond, West, Ande, Donaldson, Eric, Curtis, Kristopher, Johnston, Robert, Baric, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716185/
https://ncbi.nlm.nih.gov/pubmed/17194199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030525
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