A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store

Endoplasmic reticulum calcium homeostasis is critical for cellular functions and is disrupted in diverse pathologies including neurodegeneration and cardiovascular disease. Owing to the high concentration of calcium within the ER, studying this subcellular compartment requires tools that are optimiz...

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Udgivet i:PLoS One
Main Authors: Henderson, Mark J., Baldwin, Heather A., Werley, Christopher A., Boccardo, Stefano, Whitaker, Leslie R., Yan, Xiaokang, Holt, Graham T., Schreiter, Eric R., Looger, Loren L., Cohen, Adam E., Kim, Douglas S., Harvey, Brandon K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599735/
https://ncbi.nlm.nih.gov/pubmed/26451944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139273
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