A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store

Endoplasmic reticulum calcium homeostasis is critical for cellular functions and is disrupted in diverse pathologies including neurodegeneration and cardiovascular disease. Owing to the high concentration of calcium within the ER, studying this subcellular compartment requires tools that are optimiz...

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Veröffentlicht in:PLoS One
Hauptverfasser: Henderson, Mark J., Baldwin, Heather A., Werley, Christopher A., Boccardo, Stefano, Whitaker, Leslie R., Yan, Xiaokang, Holt, Graham T., Schreiter, Eric R., Looger, Loren L., Cohen, Adam E., Kim, Douglas S., Harvey, Brandon K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599735/
https://ncbi.nlm.nih.gov/pubmed/26451944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139273
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