A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store

Endoplasmic reticulum calcium homeostasis is critical for cellular functions and is disrupted in diverse pathologies including neurodegeneration and cardiovascular disease. Owing to the high concentration of calcium within the ER, studying this subcellular compartment requires tools that are optimiz...

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Bibliographic Details
Published in:PLoS One
Main Authors: Henderson, Mark J., Baldwin, Heather A., Werley, Christopher A., Boccardo, Stefano, Whitaker, Leslie R., Yan, Xiaokang, Holt, Graham T., Schreiter, Eric R., Looger, Loren L., Cohen, Adam E., Kim, Douglas S., Harvey, Brandon K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599735/
https://ncbi.nlm.nih.gov/pubmed/26451944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139273
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