Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice

Duchenne muscular dystrophy (DMD) is characterized by progressive lethal muscle degeneration and chronic inflammatory response. The mdx mouse strain has served as the animal model for human DMD. However, while DMD patients undergo extensive necrosis, the affected muscles of adult mdx mice rapidly re...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Pelosi, Laura, Berardinelli, Maria Grazia, Forcina, Laura, Spelta, Elisa, Rizzuto, Emanuele, Nicoletti, Carmine, Camilli, Carlotta, Testa, Erika, Catizone, Angela, De Benedetti, Fabrizio, Musarò, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599671/
https://ncbi.nlm.nih.gov/pubmed/26251044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv323
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