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Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice
Duchenne muscular dystrophy (DMD) is characterized by progressive lethal muscle degeneration and chronic inflammatory response. The mdx mouse strain has served as the animal model for human DMD. However, while DMD patients undergo extensive necrosis, the affected muscles of adult mdx mice rapidly re...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4599671/ https://ncbi.nlm.nih.gov/pubmed/26251044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv323 |
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