Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice

Duchenne muscular dystrophy (DMD) is characterized by progressive lethal muscle degeneration and chronic inflammatory response. The mdx mouse strain has served as the animal model for human DMD. However, while DMD patients undergo extensive necrosis, the affected muscles of adult mdx mice rapidly re...

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Publicado en:Hum Mol Genet
Main Authors: Pelosi, Laura, Berardinelli, Maria Grazia, Forcina, Laura, Spelta, Elisa, Rizzuto, Emanuele, Nicoletti, Carmine, Camilli, Carlotta, Testa, Erika, Catizone, Angela, De Benedetti, Fabrizio, Musarò, Antonio
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599671/
https://ncbi.nlm.nih.gov/pubmed/26251044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv323
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