Colchicine Acutely Suppresses Local Cardiac Production of Inflammatory Cytokines in Patients With an Acute Coronary Syndrome

BACKGROUND: Interleukin (IL)-1β, IL-18, and downstream IL-6 are key inflammatory cytokines in the pathogenesis of coronary artery disease. Colchicine is believed to block the NLRP3 inflammasome, a cytosolic complex responsible for the production of IL-1β and IL-18. In vivo effects of colchicine on c...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Am Heart Assoc
Hoofdauteurs: Martínez, Gonzalo J, Robertson, Stacy, Barraclough, Jennifer, Xia, Qiong, Mallat, Ziad, Bursill, Christina, Celermajer, David S, Patel, Sanjay
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley & Sons, Ltd 2015
Onderwerpen:
Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599469/
https://ncbi.nlm.nih.gov/pubmed/26304941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002128
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items