Inhibition of IGF1-R overcomes IGFBP7-induced chemotherapy resistance in T-ALL

BACKGROUND: T-cell acute lymphoblastic leukemia (T-ALL) is a genetically heterogeneous disease with the need for treatment optimization. Previously, high expression of Insulin-like growth factor binding protein 7 (IGFBP7), a member of the IGF system, was identified as negative prognostic factor in a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Bartram, Isabelle, Erben, Ulrike, Ortiz-Tanchez, Jutta, Blunert, Katja, Schlee, Cornelia, Neumann, Martin, Heesch, Sandra, Baldus, Claudia D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599323/
https://ncbi.nlm.nih.gov/pubmed/26450156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1677-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados