Mutational spectrum of adult T-ALL

Novel target discovery is warranted to improve treatment in adult T-cell acute lymphoblastic leukemia (T-ALL) patients. We provide a comprehensive study on mutations to enhance the understanding of therapeutic targets and studied 81 adult T-ALL patients. NOTCH1 exhibitedthe highest mutation rate (53...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Neumann, Martin, Vosberg, Sebastian, Schlee, Cornelia, Heesch, Sandra, Schwartz, Stefan, Gökbuget, Nicola, Hoelzer, Dieter, Graf, Alexander, Krebs, Stefan, Bartram, Isabelle, Blum, Helmut, Brüggemann, Monika, Hecht, Jochen, Bohlander, Stefan K., Greif, Philipp A., Baldus, Claudia D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413615/
https://ncbi.nlm.nih.gov/pubmed/25595890
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