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Sequence specificity between interacting and non-interacting homologs identifies interface residues – a homodimer and monomer use case

BACKGROUND: Protein families participating in protein-protein interactions may contain sub-families that have different binding characteristics, ranging from right binding to showing no interaction at all. Composition differences at the sequence level in these sub-families are often decisive to thei...

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Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Hou, Qingzhen, Dutilh, Bas E., Huynen, Martijn A., Heringa, Jaap, Feenstra, K. Anton
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599308/
https://ncbi.nlm.nih.gov/pubmed/26449222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0758-y
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