Reduction of RKIP expression promotes nasopharyngeal carcinoma invasion and metastasis by activating Stat3 signaling

The role and underlying mechanism of Raf kinase inhibitory protein (RKIP) in nasopharyngeal carcinoma (NPC) metastasis remain unclear. Here, we showed that RKIP was downregulated in the NPC with high metastatic potentials, and its decrement correlated with NPC metastasis and poor patient survival, a...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: He, Qiu-Yan, Yi, Hong-Mei, Yi, Hong, Xiao, Ta, Qu, Jia-Quan, Yuan, Li, Zhu, Jin-Feng, Li, Jiao-Yang, Wang, Yuan-Yuan, Li, Li-Na, Feng, Juan, Lu, Shan-Shan, Xiao, Zhi-Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599279/
https://ncbi.nlm.nih.gov/pubmed/25915430
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