Novel cross-talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

The insulin-like growth factor-I receptor (IGF-IR), plays a key role in regulating mammalian development and growth, and is frequently deregulated in cancer contributing to tumor initiation and progression. Discoidin domain receptor 1 (DDR1), a collagen receptor tyrosine-kinase, is as well frequentl...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Malaguarnera, Roberta, Nicolosi, Maria Luisa, Sacco, Antonella, Morcavallo, Alaide, Vella, Veronica, Voci, Concetta, Spatuzza, Michela, Xu, Shi-Qiong, Iozzo, Renato V., Vigneri, Riccardo, Morrione, Andrea, Belfiore, Antonino
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599258/
https://ncbi.nlm.nih.gov/pubmed/25840417
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