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Spotlight on decitabine for myelodysplastic syndromes in Chinese patients
Myelodysplastic syndromes (MDSs) are a group of heterogeneous clonal hematopoietic stem cell malignancies with advanced median age. The silencing of tumor suppressor genes caused by DNA hypermethylation plays a crucial role in the pathogenesis of MDS. Decitabine, the available hypomethylating agent,...
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| Опубликовано в: : | Onco Targets Ther |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Dove Medical Press
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4599041/ https://ncbi.nlm.nih.gov/pubmed/26491353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S81093 |
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