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A Novel Basal Body Protein That Is a Polo-like Kinase Substrate Is Required for Basal Body Segregation and Flagellum Adhesion in Trypanosoma brucei

The Polo-like kinase (PLK) in Trypanosoma brucei plays multiple roles in basal body segregation, flagellum attachment, and cytokinesis. However, the mechanistic role of TbPLK remains elusive, mainly because most of its substrates are not known. Here, we report a new substrate of TbPLK, SPBB1, and it...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Hu, Huiqing, Zhou, Qing, Li, Ziyin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599006/
https://ncbi.nlm.nih.gov/pubmed/26272611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.674796
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