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A Novel Basal Body Protein That Is a Polo-like Kinase Substrate Is Required for Basal Body Segregation and Flagellum Adhesion in Trypanosoma brucei

The Polo-like kinase (PLK) in Trypanosoma brucei plays multiple roles in basal body segregation, flagellum attachment, and cytokinesis. However, the mechanistic role of TbPLK remains elusive, mainly because most of its substrates are not known. Here, we report a new substrate of TbPLK, SPBB1, and it...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Hu, Huiqing, Zhou, Qing, Li, Ziyin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599006/
https://ncbi.nlm.nih.gov/pubmed/26272611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.674796
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