Impact of Adjuvants on the Immunogenicity and Efficacy of Split-Virion H7N9 Vaccine in Ferrets

Background. An effective vaccine is urgently needed against the H7N9 avian influenza virus. We evaluated the immunogenicity and protective efficacy of a split-virion H7N9 vaccine with or without the oil-in-water adjuvants in ferrets. Methods. Ferrets were vaccinated with 2 doses of unadjuvanted, MF5...

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Podrobná bibliografie
Vydáno v:J Infect Dis
Hlavní autoři: Wong, Sook-San, Kaplan, Bryan, Zanin, Mark, Debeauchamp, Jennifer, Kercher, Lisa, Crumpton, Jeri-Carol, Seiler, Patrick, Sun, Yilun, Tang, Li, Krauss, Scott, Webster, Robert, Webby, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598806/
https://ncbi.nlm.nih.gov/pubmed/25712975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv099
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