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Inhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer Therapy

Most chemotherapy regimens contain at least one DNA-damaging agent that preferentially affects the growth of cancer cells. This strategy takes advantage of the differences in cell proliferation between normal and cancer cells. Chemotherapeutic drugs are usually designed to target rapid-dividing cell...

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Podrobná bibliografie
Vydáno v:Biomolecules
Hlavní autoři: Xu, Yang, Her, Chengtao
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598769/
https://ncbi.nlm.nih.gov/pubmed/26287259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5031652
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