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Glucagon receptor inactivation leads to α-cell hyperplasia in zebrafish

Glucagon antagonism is a potential treatment for diabetes. One potential side effect is α-cell hyperplasia, which has been noted in several approaches to antagonize glucagon action. To investigate the molecular mechanism of the α-cell hyperplasia and to identify the responsible factor, we created a...

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Bibliografiska uppgifter
I publikationen:J Endocrinol
Huvudupphovsmän: Li, Mingyu, Dean, E Danielle, Zhao, Liyuan, Nicholson, Wendell E., Powers, Alvin C., Chen, Wenbiao
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598637/
https://ncbi.nlm.nih.gov/pubmed/26446275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-15-0284
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