Structure of the native Sec61 protein-conducting channel

In mammalian cells, secretory and membrane proteins are translocated across or inserted into the endoplasmic reticulum (ER) membrane by the universally conserved protein-conducting channel Sec61, which has been structurally studied in isolated, detergent-solubilized states. Here we structurally and...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Pfeffer, Stefan, Burbaum, Laura, Unverdorben, Pia, Pech, Markus, Chen, Yuxiang, Zimmermann, Richard, Beckmann, Roland, Förster, Friedrich
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598622/
https://ncbi.nlm.nih.gov/pubmed/26411746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9403
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