A carregar...
Structural Basis of Telomerase Inhibition by the Highly Specific BIBR1532
BIBR1532 is a highly specific telomerase inhibitor, however the molecular basis for inhibition is unknown. Here we present the crystal structure of BIBR1532 bound to Tribolium castaneum catalytic subunit of telomerase (tcTERT). BIBR1532 binds to a conserved hydrophobic pocket (FVYL motif) on the out...
Na minha lista:
| Publicado no: | Structure |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598299/ https://ncbi.nlm.nih.gov/pubmed/26365799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.08.006 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|