Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype

BACKGROUND: A comprehensive search for DNA methylated genes identified candidate tumor suppressor genes that have been proven to be involved in the apoptotic process of the p53 pathway. In this study, we investigated p53 mutation in relation to such epigenetic alteration in primary gastric cancer. M...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Waraya, Mina, Yamashita, Keishi, Ema, Akira, Katada, Natsuya, Kikuchi, Shiro, Watanabe, Masahiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598091/
https://ncbi.nlm.nih.gov/pubmed/26447864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139902
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