Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype

BACKGROUND: A comprehensive search for DNA methylated genes identified candidate tumor suppressor genes that have been proven to be involved in the apoptotic process of the p53 pathway. In this study, we investigated p53 mutation in relation to such epigenetic alteration in primary gastric cancer. M...

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Publicat a:PLoS One
Autors principals: Waraya, Mina, Yamashita, Keishi, Ema, Akira, Katada, Natsuya, Kikuchi, Shiro, Watanabe, Masahiko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598091/
https://ncbi.nlm.nih.gov/pubmed/26447864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139902
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