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An Sp1 Modulated Regulatory Region Unique to Higher Primates Regulates Human Androgen Receptor Promoter Activity in Prostate Cancer Cells

Androgen receptor (AR) mediated signalling is necessary for normal development of the prostate gland and also drives prostate cancer (PCa) cell growth and survival, with many studies showing a correlation between increased receptor levels and therapy resistance with progression to fatal castrate rec...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Hay, Colin W., Hunter, Irene, MacKenzie, Alasdair, McEwan, Iain J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598089/
https://ncbi.nlm.nih.gov/pubmed/26448047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139990
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