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An Sp1 Modulated Regulatory Region Unique to Higher Primates Regulates Human Androgen Receptor Promoter Activity in Prostate Cancer Cells

Androgen receptor (AR) mediated signalling is necessary for normal development of the prostate gland and also drives prostate cancer (PCa) cell growth and survival, with many studies showing a correlation between increased receptor levels and therapy resistance with progression to fatal castrate rec...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Hay, Colin W., Hunter, Irene, MacKenzie, Alasdair, McEwan, Iain J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598089/
https://ncbi.nlm.nih.gov/pubmed/26448047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139990
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