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An Sp1 Modulated Regulatory Region Unique to Higher Primates Regulates Human Androgen Receptor Promoter Activity in Prostate Cancer Cells

Androgen receptor (AR) mediated signalling is necessary for normal development of the prostate gland and also drives prostate cancer (PCa) cell growth and survival, with many studies showing a correlation between increased receptor levels and therapy resistance with progression to fatal castrate rec...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hay, Colin W., Hunter, Irene, MacKenzie, Alasdair, McEwan, Iain J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598089/
https://ncbi.nlm.nih.gov/pubmed/26448047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139990
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