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Functional Diversification of Motor Neuron-specific Isl1 Enhancers during Evolution

Functional diversification of motor neurons has occurred in order to selectively control the movements of different body parts including head, trunk and limbs. Here we report that transcription of Isl1, a major gene necessary for motor neuron identity, is controlled by two enhancers, CREST1 (E1) and...

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Pubblicato in:PLoS Genet
Autori principali: Kim, Namhee, Park, Chungoo, Jeong, Yongsu, Song, Mi-Ryoung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598079/
https://ncbi.nlm.nih.gov/pubmed/26447474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005560
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