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Synthesis and Characterization of Poly(ε-caprolactone)-block-poly[N-(2-hydroxypropyl)methacrylamide] Micelles for Drug Delivery

Amphiphilic block copolymers based on HPMA and ε-CL were synthesized by ring-opening polymerization of ε-CL followed by RAFT polymerization of HPMA. A copolymer composed of 34 kDa PHPMA and 8.5 kDa PCL associated into micelles with CMC of 5.4 μg · mL(−1). A novel retinoid, 3-Cl-AHPC-OMe, was incorpo...

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Détails bibliographiques
Publié dans:Macromol Biosci
Auteurs principaux: Krimmer, Stefan G., Pan, Huaizhong, Liu, Jihua, Yang, Jiyuan, Kopeček, Jindřich
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598047/
https://ncbi.nlm.nih.gov/pubmed/21567954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201100019
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