RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes

INTRODUCTION: RhoA has been shown to be beneficial in cardiac disease models when overexpressed in cardiomyocytes, whereas its role in cardiac fibroblasts (CF) is still poorly understood. During cardiac remodeling CF undergo a transition towards a myofibroblast phenotype thereby showing an increased...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Jatho, Aline, Hartmann, Svenja, Kittana, Naim, Mügge, Felicitas, Wuertz, Christina M., Tiburcy, Malte, Zimmermann, Wolfram-Hubertus, Katschinski, Dörthe M., Lutz, Susanne
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598021/
https://ncbi.nlm.nih.gov/pubmed/26448568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137519
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