Cystic fibrosis–adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses

Cystic fibrosis lung disease is characterized by chronic airway infections with the opportunistic pathogen Pseudomonas aeruginosa and severe neutrophilic pulmonary inflammation. P. aeruginosa undergoes extensive genetic adaptation to the cystic fibrosis (CF) lung environment, and adaptive mutations...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Adv
मुख्य लेखकों: LaFayette, Shantelle L., Houle, Daniel, Beaudoin, Trevor, Wojewodka, Gabriella, Radzioch, Danuta, Hoffman, Lucas R., Burns, Jane L., Dandekar, Ajai A., Smalley, Nicole E., Chandler, Josephine R., Zlosnik, James E., Speert, David P., Bernier, Joanie, Matouk, Elias, Brochiero, Emmanuelle, Rousseau, Simon, Nguyen, Dao
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Association for the Advancement of Science 2015
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597794/
https://ncbi.nlm.nih.gov/pubmed/26457326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500199
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