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Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication.

Transcription of type 1 human immunodeficiency virus (HIV-1) provirus is governed by the viral long terminal repeat (LTR). Drugs can block HIV-1 replication by inhibiting activity of its LTR. We report that topotecan, beta-lapachone, and curcumin are potent and selective inhibitors of HIV-1 LTR-dire...

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Bibliografske podrobnosti
Main Authors: Li, C J, Zhang, L J, Dezube, B J, Crumpacker, C S, Pardee, A B
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC45975/
https://ncbi.nlm.nih.gov/pubmed/8446597
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