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RNA sequencing reveals a depletion of collagen targeting microRNAs in Dupuytren’s disease

BACKGROUND: Dupuytren’s disease is an inherited disorder in which patients develop fibrotic contractures of the hand. Current treatment strategies include surgical excision or enzymatic digestion of fibrotic tissue. MicroRNAs, which are key posttranscriptional regulators of genes expression, have be...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Riester, Scott M., Arsoy, Diren, Camilleri, Emily T., Dudakovic, Amel, Paradise, Christopher R., Evans, Jared M., Torres-Mora, Jorge, Rizzo, Marco, Kloen, Peter, Julio, Marianna Kruithof-de, van Wijnen, Andre J., Kakar, Sanjeev
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597401/
https://ncbi.nlm.nih.gov/pubmed/26446724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0135-8
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