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Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data
BACKGROUND: Adapter trimming and removal of duplicate reads are common practices in next-generation sequencing pipelines. Sequencing reads ambiguously mapped to repetitive and low complexity regions can also be problematic for accurate assessment of the biological signal, yet their impact on sequenc...
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| Publicado no: | BMC Bioinformatics |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4597324/ https://ncbi.nlm.nih.gov/pubmed/26423047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S13-S10 |
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