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Evolving Catalytic Properties of the MLL Family SET Domain
Methylation of histone H3 lysine-4 is a hallmark of chromatin associated with active gene expression. The activity of H3K4-specific modification enzymes, in higher eukaryotes the MLL (or KMT2) family, is tightly regulated. The MLL family has six members, each with a specialized function. All contain...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4597100/ https://ncbi.nlm.nih.gov/pubmed/26320581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.07.018 |
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