Cytokeratin-20 and Survivin Expressing Circulating Tumor Cells Predict Survival in Metastatic Colorectal Cancer Patients by a Combined Immunomagnetic qRT-PCR Approach

Circulating tumor cells (CTCs) express epithelial and stem cell like genes, though current approved detection methods mainly employ epithelial markers. We optimized a CTC isolation method which could capture their molecular heterogeneity and predict overall survival (OS) in metastatic CRC (mCRC) pat...

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發表在:Mol Cancer Ther
Main Authors: Ning, Yan, Hanna, Diana L, Zhang, Wu, Mendez, Angela, Yang, Dongyun, El-Khoueiry, Rita, Matsusaka, Satoshi, Sunakawa, Yu, Stremitzer, Stefan, Parekh, Anish, Okazaki, Satoshi, Berger, Martin D., Barzi, Afsaneh, Lenz, Heinz-Josef
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596790/
https://ncbi.nlm.nih.gov/pubmed/26227487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0359
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