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Cytokeratin-20 and Survivin Expressing Circulating Tumor Cells Predict Survival in Metastatic Colorectal Cancer Patients by a Combined Immunomagnetic qRT-PCR Approach
Circulating tumor cells (CTCs) express epithelial and stem cell like genes, though current approved detection methods mainly employ epithelial markers. We optimized a CTC isolation method which could capture their molecular heterogeneity and predict overall survival (OS) in metastatic CRC (mCRC) pat...
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Publicado no: | Mol Cancer Ther |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4596790/ https://ncbi.nlm.nih.gov/pubmed/26227487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0359 |
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