R-ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis

Cdc42 (cell division control protein 42) and Rac1 (Ras-related C3 botulinum toxin substrate 1) are attractive therapeutic targets in ovarian cancer based on established importance in tumor cell migration, adhesion and invasion. Despite a predicted benefit, targeting GTPases has not yet been translat...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Ther
Asıl Yazarlar: Guo, Yuna, Kenney, Shelby Ray, Muller, Carolyn Y., Adams, Sarah, Rutledge, Teresa, Romero, Elsa, Murray-Krezan, Cristina, Prekeris, Rytis, Sklar, Larry A., Hudson, Laurie G., Wandinger-Ness, Angela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596774/
https://ncbi.nlm.nih.gov/pubmed/26206334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0419
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