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Intrapulmonary Delivery of CpG Microparticles Eliminates Lung Tumors

CpG oligonucleotides (ODN) stimulate the innate immune system by triggering cells that express TLR9. The resulting response promotes tumor regression, an effect optimized by delivery of CpG ODN to the tumor site. This work examines the effect of instilling CpG ODN adsorbed onto polyketal micropartic...

詳細記述

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書誌詳細
出版年:Mol Cancer Ther
主要な著者: Sato, Takashi, Shimosato, Takeshi, Ueda, Atsuhisa, Ishigatsubo, Yoshiaki, Klinman, Dennis M
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596766/
https://ncbi.nlm.nih.gov/pubmed/26206336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0401
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