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Intrapulmonary Delivery of CpG Microparticles Eliminates Lung Tumors

CpG oligonucleotides (ODN) stimulate the innate immune system by triggering cells that express TLR9. The resulting response promotes tumor regression, an effect optimized by delivery of CpG ODN to the tumor site. This work examines the effect of instilling CpG ODN adsorbed onto polyketal micropartic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cancer Ther
Päätekijät: Sato, Takashi, Shimosato, Takeshi, Ueda, Atsuhisa, Ishigatsubo, Yoshiaki, Klinman, Dennis M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596766/
https://ncbi.nlm.nih.gov/pubmed/26206336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0401
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