CD98 Heavy Chain Is a Potent Positive Regulator of CD4(+) T Cell Proliferation and Interferon-γ Production In Vivo

Upon their recognition of antigens presented by the MHC, T cell proliferation is vital for clonal expansion and the acquisition of effector functions, which are essential for mounting adaptive immune responses. The CD98 heavy chain (CD98hc, Slc3a2) plays a crucial role in the proliferation of both C...

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Udgivet i:PLoS One
Main Authors: Kurihara, Takeshi, Arimochi, Hideki, Bhuyan, Zaied Ahmed, Ishifune, Chieko, Tsumura, Hideki, Ito, Morihiro, Ito, Yasuhiko, Kitamura, Akiko, Maekawa, Yoichi, Yasutomo, Koji
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596652/
https://ncbi.nlm.nih.gov/pubmed/26444422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139692
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