Study of the Chemotactic Response of Multicellular Spheroids in a Microfluidic Device

We report the first application of a microfluidic device to observe chemotactic migration in multicellular spheroids. A microfluidic device was designed comprising a central microchamber and two lateral channels through which reagents can be introduced. Multicellular spheroids were embedded in colla...

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Udgivet i:PLoS One
Main Authors: Ayuso, Jose M., Basheer, Haneen A., Monge, Rosa, Sánchez-Álvarez, Pablo, Doblaré, Manuel, Shnyder, Steven D., Vinader, Victoria, Afarinkia, Kamyar, Fernández, Luis J., Ochoa, Ignacio
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596573/
https://ncbi.nlm.nih.gov/pubmed/26444904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139515
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