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Leptin Is Required for Glucose Homeostasis after Roux-en-Y Gastric Bypass in Mice

BACKGROUND & AIMS: Leptin, the protein product of the ob gene, increases energy expenditure and reduces food intake, thereby promoting weight reduction. Leptin also regulates glucose homeostasis and hepatic insulin sensitivity via hypothalamic proopiomelanocortin neurons in mice. Roux-en-Y gastr...

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Publicat a:PLoS One
Autors principals: Mokadem, Mohamad, Zechner, Juliet F., Uchida, Aki, Aguirre, Vincent
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596552/
https://ncbi.nlm.nih.gov/pubmed/26445459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139960
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