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Leptin Is Required for Glucose Homeostasis after Roux-en-Y Gastric Bypass in Mice

BACKGROUND & AIMS: Leptin, the protein product of the ob gene, increases energy expenditure and reduces food intake, thereby promoting weight reduction. Leptin also regulates glucose homeostasis and hepatic insulin sensitivity via hypothalamic proopiomelanocortin neurons in mice. Roux-en-Y gastr...

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發表在:PLoS One
Main Authors: Mokadem, Mohamad, Zechner, Juliet F., Uchida, Aki, Aguirre, Vincent
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596552/
https://ncbi.nlm.nih.gov/pubmed/26445459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139960
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