Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency()()()

Glucagon-like peptide-1 (GLP-1) secretion is greatly enhanced after Roux-en-Y gastric bypass (RYGB). While intact GLP-1exerts its metabolic effects via the classical GLP-1 receptor (GLP-1R), proteolytic processing of circulating GLP-1 yields metabolites such as GLP-1(9–36)amide/GLP-1(28–36)amide, th...

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Autori principali: Mokadem, Mohamad, Zechner, Juliet F., Margolskee, Robert F., Drucker, Daniel J., Aguirre, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953682/
https://ncbi.nlm.nih.gov/pubmed/24634822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.11.010
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