Up-regulation of miR-130b expression level and down-regulation of miR-218 serve as potential biomarker in the early detection of human osteosarcoma

BACKGROUND: Osteosarcoma (OS) is a primary malignant bone tumor with high morbidity that principally emerges in children and adolescents. MiRNAs regulate a variety of normal physiologic processes and are involved in tumorigenesis and development of multiple malignancies, including OS. This study was...

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Bibliographic Details
Published in:Diagn Pathol
Main Authors: Taheriazam, Afshin, Talaei, Amir Jouya, Jamshidi, Mohammad, Shakeri, Mohammadreza, Khoshbakht, Samaneh, Yahaghi, Emad, Shokrani, Marjan
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596511/
https://ncbi.nlm.nih.gov/pubmed/26446495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-015-0422-x
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