Down-regulation of microRNA-26a and up-regulation of microRNA-27a contributes to aggressive progression of human osteosarcoma

BACKGROUND: Osteosarcoma is the most common primary bone malignancy with high local aggressiveness and rapid metastasizing potential, resulting in poor survival. Increasing reports suggest that deregulated microRNAs (miRNAs) might provide novel therapeutic targets for cancers. However, the expressio...

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Veröffentlicht in:Diagn Pathol
Hauptverfasser: Taheriazam, Afshin, Bahador, Reza, Karbasy, Seyyed Hasan, Jamshidi, Seyed Mir Mansoor Moazen, Torkaman, Ali, Yahaghi, Emad, Shakeri, Mohammadreza
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573687/
https://ncbi.nlm.nih.gov/pubmed/26377680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-015-0400-3
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