HIV–tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling

Patients with HIV-associated tuberculosis (TB) initiating antiretroviral therapy (ART) may develop immune reconstitution inflammatory syndrome (TB-IRIS). No biomarkers for TB-IRIS have been identified and the underlying mechanisms are unclear. Here we perform transcriptomic profiling of the blood sa...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lai, Rachel P. J., Meintjes, Graeme, Wilkinson, Katalin A., Graham, Christine M., Marais, Suzaan, Van der Plas, Helen, Deffur, Armin, Schutz, Charlotte, Bloom, Chloe, Munagala, Indira, Anguiano, Esperanza, Goliath, Rene, Maartens, Gary, Banchereau, Jacques, Chaussabel, Damien, O'Garra, Anne, Wilkinson, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595995/
https://ncbi.nlm.nih.gov/pubmed/26399326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9451
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