Dissolution Rate Enhancement, Design and Development of Buccal Drug Delivery of Darifenacin Hydroxypropyl β-Cyclodextrin Inclusion Complexes

Darifenacin is a urinary antispasmodic. The oral absorption of darifenacin is poor due to its low solubility and poor bioavailability (15–19%). Darifenacin was complexed with hydroxylropyl beta-cyclodextrin (Hpβ-CD). The best results were obtained with the coevaporation that interacts in a 1 : 1 dru...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Pharm (Cairo)
Autores principales: Jagdale, Swati C., Mohanty, Prachyasuman, Chabukswar, Aniruddha R., Kuchekar, Bhanudas S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595963/
https://ncbi.nlm.nih.gov/pubmed/26556003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/983702
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares