Dissolution Rate Enhancement, Design and Development of Buccal Drug Delivery of Darifenacin Hydroxypropyl β-Cyclodextrin Inclusion Complexes

Darifenacin is a urinary antispasmodic. The oral absorption of darifenacin is poor due to its low solubility and poor bioavailability (15–19%). Darifenacin was complexed with hydroxylropyl beta-cyclodextrin (Hpβ-CD). The best results were obtained with the coevaporation that interacts in a 1 : 1 dru...

Full description

Saved in:
Bibliographic Details
Published in:J Pharm (Cairo)
Main Authors: Jagdale, Swati C., Mohanty, Prachyasuman, Chabukswar, Aniruddha R., Kuchekar, Bhanudas S.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595963/
https://ncbi.nlm.nih.gov/pubmed/26556003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/983702
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items