Generation and Analysis of Genetically Defined Liver Carcinomas Derived from Bipotential Liver Progenitors

Hepatocellular carcinoma is a chemoresistant cancer and a leading cause of cancer mortality; however, the molecular mechanisms responsible for the aggressive nature of this disease are poorly understood. In this study, we developed a new liver cancer mouse model that is based on the ex vivo genetic...

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Udgivet i:Cold Spring Harb Symp Quant Biol
Main Authors: ZENDER, L., XUE, W., CORDÓN-CARDO, C., HANNON, G.J., LUCITO, R., POWERS, S., FLEMMING, P., SPECTOR, M.S., LOWE, S.W.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595853/
https://ncbi.nlm.nih.gov/pubmed/16869761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2005.70.059
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