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Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice.

The mouse lpr (lymphoproliferation) mutation carries a rearrangement in the chromosomal gene for the Fas antigen, which mediates apoptosis. Isolation and characterization of mouse Fas antigen chromosomal gene from wild-type and lpr mice indicated an insertion of an early transposable element (ETn) i...

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Detalles Bibliográficos
Main Authors: Adachi, M, Watanabe-Fukunaga, R, Nagata, S
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC45958/
https://ncbi.nlm.nih.gov/pubmed/7680478
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