Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact

Individuals with Angelman syndrome (AS) suffer sleep disturbances that severely impair quality of life. Whether these disturbances arise from sleep or circadian clock dysfunction is currently unknown. Here, we explored the mechanistic basis for these sleep disorders in a mouse model of Angelman synd...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ehlen, J. Christopher, Jones, Kelly A., Pinckney, Lennisha, Gray, Cloe L., Burette, Susan, Weinberg, Richard J., Evans, Jennifer A., Brager, Allison J., Zylka, Mark J., Paul, Ketema N., Philpot, Benjamin D., DeBruyne, Jason P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595617/
https://ncbi.nlm.nih.gov/pubmed/26446213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2194-15.2015
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